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NOT YET RECRUITING
NCT07881952
PHASE2

Safety and Systemic Exposure of YCANTH (VP-102) in Subjects With Common Warts (Verruca Vulgaris) (COVE-5)

Sponsor: Verrica Pharmaceuticals Inc.

View on ClinicalTrials.gov

Summary

This is a Phase 2, open-label study (Study VP-CW-304; referred to as COVE-5 \[Cantharidin and Occlusion in Verruca Epithelium 5\]) to evaluate the safety and systemic exposure of YCANTH (VP-102) following a single 24-hour dermal application in subjects with common warts.

Official title: COVE-5: A Phase 2, Open-label Study to Evaluate the Safety and Systemic Exposure of YCANTH (VP-102) in Subjects With Common Warts (Verruca Vulgaris)

Key Details

Gender

All

Age Range

2 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2026-10

Completion Date

2027-04

Last Updated

2026-10-20

Healthy Volunteers

No

Interventions

COMBINATION_PRODUCT

VP-102

YCANTH (VP-102) is supplied as a topical solution containing cantharidin 0.7% w/v in a single-use glass ampule applicator. The solution will be applied to the entirety of each common wart selected for treatment, including an approximate 1 to 2 mm margin of surrounding healthy skin. No more than 2 applicators may be used. Occlusive tape will be applied after the solution has dried and will remain in place overnight until removal at approximately 24 hours.

Locations (4)

Equity Medical Bowling Green

Bowling Green, Kentucky, United States

Equity Medical Owensboro

Owensboro, Kentucky, United States

Equity Medical Manhattan

New York, New York, United States

Equity Medical Bronx

The Bronx, New York, United States