Clinical Research Directory
Browse clinical research sites, groups, and studies.
Immediate vs Conventional Loading With Different Crown Materials on Immediately Placed Single Implants
Sponsor: Ain Shams University
Summary
This randomized controlled trial compares immediate and conventional loading of single implants placed immediately into fresh extraction sockets in the upper front and premolar region. Eighty adults will be randomly assigned to four groups: immediate loading (within 48 hours) with a definitive zirconia crown, a permanent printed PMMA crown, or a temporary printed PMMA crown, or conventional loading with a definitive zirconia crown after 3 months. All implants are placed with a fully guided digital workflow.
Official title: Impact of Loading Protocol (Immediate vs. Conventional) and Prosthetic Material (Temporary vs. Definitive) on the Clinical Outcomes of Immediately Placed Implants: A Randomized Controlled Comparative Study
Key Details
Gender
All
Age Range
21 Years - 50 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2026-11-25
Completion Date
2028-03-25
Last Updated
2026-10-20
Healthy Volunteers
No
Conditions
Interventions
Conventional loading
Cover screw and 3 months of unloaded healing, then a screw-retained crown in full occlusion.
Monolithic zirconia crown
CAD-CAM milled monolithic zirconia (Zolid fx, Amann Girrbach) screw-retained crown on a Ti-base.
Permanent 3D-printed PMMA crown
DLP-printed (AccuFab D1s) permanent PMMA-based resin crown on a Ti-base.
Temporary 3D-printed PMMA crown
DLP-printed (AccuFab D1s) provisional PMMA-based resin crown on a Ti-base.
Locations (2)
Assiut University
Asyut, Asyut Governorate, Egypt
Ain Shams University
Cairo, Cairo Governorate, Egypt