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NOT YET RECRUITING
NCT07883083
NA

Closed Versus Open Endotracheal Suctioning and Ventilator-Associated Pneumonia in Severe Traumatic Brain Injury

Sponsor: Minia University

View on ClinicalTrials.gov

Summary

This randomized controlled trial will compare closed versus open endotracheal suctioning techniques for preventing ventilator-associated pneumonia (VAP) in adults with severe traumatic brain injury (TBI) who need mechanical ventilation for more than 48 hours. Patients will be randomly assigned to suctioning with a closed in-line system or with a sterile open technique that disconnects the ventilator. The main outcome is the incidence density of VAP per 1,000 ventilator-days. Other outcomes include oxygenation after suctioning, duration of mechanical ventilation, intensive care unit (ICU) length of stay, and ICU mortality.

Official title: Impact of Closed Versus Open Endotracheal Suctioning Techniques on the Incidence of Ventilator-Associated Pneumonia in Patients With Severe Traumatic Brain Injury

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2026-10-04

Completion Date

2027-05-30

Last Updated

2026-10-20

Healthy Volunteers

No

Interventions

DEVICE

Closed endotracheal suction system

In-line closed suction catheter system that allows endotracheal suctioning without disconnecting the ventilator.

PROCEDURE

Open endotracheal suction

Endotracheal suctioning using sterile disposable catheters with ventilator disconnection during the procedure.

Locations (1)

Minia university hospital

Minya, Egypt