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Modified Thoracolumbar Interfascial Plane Block vs Retrolaminar Block for Pain in Lumbar Spine Surgeries
Sponsor: Zagazig University
Summary
This prospective randomized double-blind study aims to compare the efficacy of modified Thoracolumbar Interfascial Plane (mTLIP) block versus Retrolaminar block for postoperative pain control in patients undergoing elective two-level lumbar spine surgeries. The primary outcome is total morphine consumption in the first 24 postoperative hours.
Official title: Effect of Modified Thoracolumbar Interfascial Plane Block Versus Retrolaminar Block for Pain Control in Postoperative Lumbar Spine Surgeries: A Prospective Randomized Double-Blind Clinical Study
Key Details
Gender
All
Age Range
21 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
42
Start Date
2025-10-01
Completion Date
2027-01-01
Last Updated
2026-10-20
Healthy Volunteers
No
Conditions
Interventions
Morphine
Rescue analgesic administered intravenously at a dose of 0.1-0.2 mg/kg every 2-4 hours as needed for breakthrough pain (NRS \> 3), with a maximum dose of 10 mg per administration.
Bupivacaine
Local anesthetic used in the block solution (0.25%, 15 mL per side).
Dexamethasone
Adjuvant added to the block solution (8 mg per side) to prolong analgesia.
Magnesium Sulphate
Adjuvant added to the block solution (300 mg of 10% per side) to prolong analgesia.
Modified Thoracolumbar Interfascial Plane Block
Ultrasound-guided injection between the longissimus and iliocostalis muscles at the L3 level.
Retrolaminar Block
Ultrasound-guided injection on the posterior surface of the vertebral lamina at the L3 level, deep to the erector spinae muscles.
Locations (1)
Zagazig University Hospitals, Anesthesia, Intensive Care and Pain Management Department
Zagazig, Sharqia Province, Egypt