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Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer
Sponsor: Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Summary
Perioperative immunonutrition has been proposed as a strategy to modulate the inflammatory response and improve outcomes after upper GI surgery. However, clinical evidence is heterogeneous, and there are few studies that integrate morbidity outcomes with objective measures of body composition using computed tomography (CT). The objective was to compare immunonutrition versus standard enteral supplementation in surgically treated patients with upper GI cancer (gastric, esophageal, pancreatic), evaluating postoperativecomplications and changes in body composition.
Official title: Nutritional Therapy in the Surgical Prehabilitation of Patients With Esophageal, Gastric, and Pancreatic Cancer to Assess the Reduction of Postoperative Complications and the Maintenance of Muscle Mass.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
110
Start Date
2026-01-01
Completion Date
2028-07-01
Last Updated
2026-10-20
Healthy Volunteers
No
Conditions
Interventions
Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid)
Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid)
Standart of care
Standard oral nutritional supplements if needed guided by usual practice hospital protocol.
Locations (1)
Hospital Universitario Ramón y Cajal
Madrid, Spain