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Temporal Dynamics of Peripheral SpO₂ During Reoxygenation
Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Summary
Pulse oximeters estimate arterial oxyhaemoglobin saturation (SaO₂) from photoplethysmographic signals recorded at peripheral sites (usually the fingertip), thus measuring the peripheral oxygen saturation (SpO₂). They are ubiquitous in emergency medicine because they offer a non-invasive, continuous measure of oxygenation and can alert clinicians to impending hypoxaemia, both during procedures such as rapid sequence intubation or sedation, or for continuous monitoring of patients. However, the accuracy of SpO₂ is often assumed to be instantaneous. This assumption is particularly hazardous during critical events involving rapid desaturation and resaturation. In such situations clinicians use SpO₂ readings to decide when to stop an apnea period during laryngoscopy and commence reoxygenation. If there is a delay between actual arterial desaturation and the displayed SpO₂, the clinician may not recognise hypoxaemia in time or may resume ventilation too late.
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2026-08-03
Completion Date
2027-02-01
Last Updated
2026-10-20
Healthy Volunteers
Yes
Conditions
Interventions
Voluntary Apnea
Two pulse oximetry sensors (finger and earlobe) will be simultaneously applied, and baseline oxygen saturation (SpO₂), heart rate, and perfusion index will be recorded. The participant will then perform two voluntary apnea tests, during which these parameters will be continuously monitored to assess the timing of apnea, desaturation, nadir, and resaturation.
Locations (1)
Cliniques Universitaires Saint-Luc
Brussels, Belgium