Clinical Research Directory

Inclusion Criteria: * I1. Patients ≥ 18 years at the day of signing informed consent. * I2. Patients referred for upper gastrointestinal endoscopy due to upper GI symptoms such as dysphagia, unexplained anemia, persistent dyspepsia or melena or following initial GEC diagnosis in another institution. * I3. Patients who have understood, dated, and signed the written voluntary informed consent form. * I4. Patients affiliated with or benefiting from medical insurance. Exclusion Criteria: * E1. Patients with known active malignancy. Exceptions include adequately treated basal cell carcinoma of the skin, squamous cell carcinoma of the skin, or in situ cervical cancer. * E2. Patients with known genetic predisposition such as Lynch syndrome or hereditary diffuse gastric cancer. * E3. Any condition contraindicating any procedure required by the protocol. * E4. Patients presenting a psychological, familial, geographical, or social situation that, in the investigator's judgment, could potentially prevent the signing of informed consent and/or compliance with study procedures. * E5. Pregnant or breast-feeding women.