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The Impact of Early-life Organic Feeding on Infants' Health: A Cluster Randomized Controlled Trial
Sponsor: Tsinghua University
Summary
This completed study compared early-life feeding with organic infant formula and organic complementary foods, conventional infant formula and conventional complementary foods, and breastfeeding with family-selected complementary foods. Infants were recruited in Chenzhou, Hunan, China, and followed through 8 months of age. The study examined physical growth, early development, gastrointestinal symptoms, stool characteristics, and gut microbiota. Measurements and questionnaires were collected at baseline and scheduled visits at 2, 4, 6, and 8 months of age. The aim was to assess whether organic feeding was associated with differences in infant health and gut microbiota compared with conventional feeding, with breastfeeding as a natural reference. Registration is being completed retrospectively after the study has finished.
Key Details
Gender
All
Age Range
0 Months - 2 Months
Study Type
INTERVENTIONAL
Enrollment
71
Start Date
2022-04-22
Completion Date
2023-09-24
Last Updated
2026-10-21
Healthy Volunteers
Yes
Interventions
Organic infant formula and organic complementary foods
Age-appropriate organic infant formula and organic complementary foods were provided according to the feeding schedule described for the Organic Feeding Group.
Conventional infant formula and conventional complementary foods
Age-appropriate conventional infant formula and conventional complementary foods were provided according to the feeding schedule described for the Conventional Feeding Group.
Locations (3)
Chenzhou Maternal and Child Health Hospital (Main Campus)
Chenzhou, Hunan, China
Chenzhou Maternal and Child Health Hospital (Suxian Campus)
Chenzhou, Hunan, China
Guiyang Maternal and Child Health Hospital
Chenzhou, Hunan, China