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Computed Inspiratory Muscle Pressure to Monitor Inspiratory Effort During Pressure Support Ventilation
Sponsor: Jian-Xin Zhou
Summary
The goal of this study is to validate computed inspiratory muscle pressure (cPmus) for monitoring inspiratory effort in adults receiving pressure support ventilation. Researchers will compare cPmus with reference inspiratory muscle pressure calculated using an esophageal balloon catheter, a thin pressure-measuring tube placed in the esophagus. The study will look at how closely the two methods are related and whether they give similar results. Participants will undergo simultaneous monitoring with cPmus and an esophageal balloon catheter. Researchers will adjust pressure support across six levels, recording measurements from both methods at each level.
Official title: Validation of Computed Inspiratory Muscle Pressure to Monitor Inspiratory Effort During Pressure Support Ventilation: A Prospective Physiological Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-11-01
Completion Date
2027-04-30
Last Updated
2026-10-21
Healthy Volunteers
No
Conditions
Interventions
Pressure support 15
Pressure support of 15 cm H2O will be applied for 10 minutes.
Pressure support 13
Pressure support of 13 cm H2O will be applied for 10 minutes.
Pressure support 11
Pressure support of 11 cm H2O will be applied for 10 minutes.
Pressure support 9
Pressure support of 9 cm H2O will be applied for 10 minutes.
Pressure support 7
Pressure support of 7 cm H2O will be applied for 10 minutes.
Pressure support 5
Pressure support of 5 cm H2O will be applied for 10 minutes.
Locations (1)
Beijing Shijitan Hospital
Beijing, China