Clinical Research Directory

Inclusion Criteria: * Adult patient (≥ 18 years old) hospitalized for aortic, coronary, ascending aortic or combined valvular heart surgery * Patient understands French * Patient affiliated with the French Social Security * Patient has given a written informed consent Exclusion Criteria: * Patient who are part of a vulnerable population (including pregnant women and patients under guardianship or trusteeship) * Current treatment by amiodarone or colchicine * Patient who will receive emergency surgery (\< 24h) * Patient who will receive mitral or tricuspid valve surgery * Patient who will receive Transcatheter Aortic Valve Implantation (TAVI) * Patient with active sepsis (endocarditis) * Patient with a history of atrial fibrillation * Patient who refuses access to his/her personal data for quality control * Patient treated with immunosuppressive therapy (for example cyclosporine) * Women of childbearing potential who are sexually active in a heterosexual relationship and not using a highly effective method of contraception * Patient presenting a contraindication to the posterior pericardial window * Patient presenting a contraindication to colchicine * Patient presenting a contraindication to amiodarone * Known hypersensitivity to iodine or amiodarone or any of the excipients listed in the SmPC * Breastfeeding * Patients under treatment with drugs that interact with amiodarone