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RECRUITING
NCT07887178
NA

Methyl Donor-Rich Diet in the Postpartum Period

Sponsor: Istanbul University - Cerrahpasa

View on ClinicalTrials.gov

Summary

This study aims to evaluate the effects of a methyl-donor-rich diet during the postpartum period on maternal depression, breastfeeding success, and infant weight. Postpartum women will first complete a three-day dietary record to assess their intake of selected nutrients involved in one-carbon metabolism, including folate, choline, betaine, methionine, vitamin B6, and vitamin B12. Women whose intake of at least one of these nutrients is below two-thirds of the applicable reference intake and who meet the other eligibility criteria will be eligible to participate. Eligible participants will be randomly assigned to one of two groups. The intervention group will receive an individualized methyl-donor-rich dietary program and nutrition education for two months. The control group will receive standard postpartum care and routine dietary advice. The study will compare the groups in terms of maternal depressive symptoms, breastfeeding success, and infant weight. Dietary intake will also be assessed.

Official title: The Effect of a Methyl Donor-Rich Diet in the Postpartum Period on Maternal Depression Levels, Breastfeeding Success and Infant Weight: A Randomized Controlled Trial

Key Details

Gender

FEMALE

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-05-21

Completion Date

2027-12

Last Updated

2026-10-21

Healthy Volunteers

No

Interventions

BEHAVIORAL

Methyl Donor-Rich Dietary Intervention

An individualized methyl-donor-rich dietary program and nutrition education will be provided for two months. The intervention will focus on increasing the dietary intake of folate, choline, betaine, methionine, vitamin B6, and vitamin B12 through food-based dietary modifications without supplementation. Kitchen scales will be provided to support portion-size education.

Locations (1)

Orhaneli Merkez Aile Sağlığı Merkezi

Bursa, Orhaneli̇, Turkey (Türkiye)