Clinical Research Directory

Inclusion Criteria: * Patients with chronic kidney disease experiencing intradialytic fatigue who are undergoing routine hemodialysis twice weekly for at least 6 months and are hemodynamically stable (blood pressure ≥90/60 mmHg and heart rate of 60-100 beats/minute). * Participants aged 18-59 years. * Participants who have not received acupuncture therapy for at least one month prior to the study. * Participants who are willing to participate in the study according to the scheduled protocol until completion and who provide written informed consent. Exclusion Criteria: * Participants with malignancies or infected wounds at the acupuncture points targeted for intervention. * Participants with primary skin diseases, such as allergic dermatitis, irritant contact dermatitis, neurodermatitis, and psoriasis. * Participants with a history of hypersensitivity reactions to previous acupuncture therapy, including stainless steel allergy, atopy, keloid formation, or other hypersensitivity reactions. * Participants receiving cognitive behavioral therapy (CBT) or psychiatric medications within two weeks prior to the study.