Clinical Research Directory

Inclusion Criteria: * Documented episode of sepsis or septic shock requiring hospitalization and treatment in an intensive care unit (ICU). * Sequential Organ Failure Assessment (SOFA) score ≥4 points during the ICU stay * Discharge from the ICU and hospital after completion of treatment for sepsis or septic shock * Montreal Cognitive Assessment (MoCA) score ≥26 points * Availability for remote follow-up during the 1-year post-sepsis period following hospital discharge * Ability to participate in remote visits, complete remote questionnaires (PROMIS questionnaire, depression and anxiety rating scales), and transmit them via electronic communication means. * Ability to understand and independently complete patient-reported outcome questionnaires, or to complete them with minimal assistance. * Availability of information regarding whether hemoadsorption with Efferon® LPS was performed during hospitalization for sepsis or septic shock * Signed informed consent for participation in the study and collection of follow-up data Exclusion Criteria: * Severe cognitive impairment, dementia, or other conditions that prevent the participant from understanding the questionnaire items and providing meaningful responses. * Severe mental illness or other psychiatric conditions that, in the Investigator's opinion, may substantially affect the validity or reliability of patient-reported outcomes. * Inability to maintain remote contact with the participant during the follow-up period. * Palliative care status. * Current participation in another clinical study that, in the Investigator's opinion, may affect the quality-of-life or psychological outcomes assessed in this study. * Any other condition or circumstance that, in the Investigator's opinion, may interfere with the participant's ability to comply with study procedures or may compromise the reliability of the study data