Clinical Research Directory
Browse clinical research sites, groups, and studies.
Dermis on Demand Allograft Augmentation for Rotator Cuff Repair
Sponsor: University of Cincinnati
Summary
The purpose of this study is to find out whether adding a human acellular dermal allograft (Dermis on Demand) during arthroscopic rotator cuff repair improves tendon-to-bone healing and lowers the rate of re-tear compared to standard repair alone. Sixty adults with large (3-5 cm) full-thickness superior or posterosuperior rotator cuff tears will be randomly assigned to repair with or without the allograft. Healing will be assessed by MRI at 12 months and by ultrasound at 6 months after surgery. Patient-reported outcomes, shoulder range of motion and strength, and operative time will also be compared between the groups.
Official title: A Randomized Control Trial Assessing the Efficacy of the Dermis on Demand for Rotator Cuff Repair
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2021-12-02
Completion Date
2026-05-15
Last Updated
2026-10-22
Healthy Volunteers
No
Conditions
Interventions
Arthroscopic rotator cuff repair; Biological: Dermis on Demand
Arthroscopic knotless double-row transosseous-equivalent rotator cuff repair augmented with 2-3 Dermis on Demand acellular dermal allograft pieces loaded onto lateral-row suture tapes
Arthroscopic rotator cuff repair
A human acellular dermal allograft (CellRight Technologies) with a cannulated design, loaded onto suture tape and compressed onto the repaired footprint during lateral-row anchor seating. Other names: DOD; acellular dermal allograft.
Locations (1)
University of Cincinnati / UC Health Orthopaedics & Sports Medicine
Cincinnati, Ohio, United States