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Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
Sponsor: Ugur Duman
Summary
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery. The main question it aims to answer is: * Is greater cumulative exposure to increased abdominal pressure associated with a higher risk of acute kidney injury? Participants will have abdominal pressure measured through a urinary catheter during routine intensive care. Researchers will record these measurements and information about kidney function without changing participants' treatment.
Official title: Predictive Value of Cumulative Intra-Abdominal Pressure Burden for Acute Kidney Injury in Critically Ill Patients Following Emergency Abdominal Surgery: A Prospective Observational Cohort Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2026-12-01
Completion Date
2027-11-30
Last Updated
2026-10-23
Healthy Volunteers
No
Interventions
Serial Intra-Abdominal Pressure Measurement
Intra-abdominal pressure will be measured serially during the first 48 postoperative hours using the intravesical pressure measurement technique through a urinary catheter. Mean arterial pressure will be recorded simultaneously, and abdominal perfusion pressure will be calculated as MAP minus IAP. Cumulative IAP, APP, and MAP burden parameters will be derived from serial measurements. These assessments will be observational and will not influence clinical treatment decisions.
Locations (1)
Bursa Yuksek Ihtisas Training and Research Hospital
Bursa, Turkey (Türkiye)