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Effect of Transcutaneous Electrical Stimulation on Polysomnographic Parameters in Patients With Obstructive Sleep Apnea
Sponsor: Mansoura University
Summary
* The aim of this study is to assess the impact of transcutaneous electrical stimulation on polysomnographic findings in obstructive sleep apnea patients. * The hypothesis of the present study is that nocturnal delivery of transcutaneous electrical stimulation of the pharyngeal dilators, in particular the genioglossus, may help in treating the functional loss of the neuromuscular tone with sleep onset to keep the Upper airway patent during sleep which would reduce the severity of OSA as measured by the apnea-hypopnea-index (AHI), so representing an alternative and better-tolerated approach compared to usual care with CPAP.
Official title: Effect of Transcutaneous Electrical Stimulation on Polysomnographic Parameters in Patients With Obstructive Sleep Apnea: A Prospective Interventional Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2025-07-06
Completion Date
2027-02
Last Updated
2026-10-23
Healthy Volunteers
No
Conditions
Interventions
Transcutaneous Electrical Stimulation
Transcutaneous electrical stimulation will be delivered using an EV-906 Digital TENS/EMS device. Two 4 × 4 cm electrode patches will be placed bilaterally over the submental region, approximately halfway between the chin and the angle of the mandible. Stimulation will use a pulsed, symmetric, biphasic waveform at a frequency of 30 Hz and a phase duration of 200 microseconds, with 5-second ON and 5-second OFF cycles. Stimulation intensity will be titrated while the participant is awake to establish a tolerable sensory level. The intervention will be administered during the second overnight polysomnography session to assess its effects on polysomnographic parameters in patients with obstructive sleep apnea.
Locations (1)
Mansoura University
Al Mansurah, Dakahlia Governorate, Egypt