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Purse-String Versus Linear Closure After Ileostomy Reversal
Sponsor: Dnipro Regional Clinical Oncology Dispensary
Summary
This randomized study compared two wound closure and wound care protocols after reversal of a diverting ileostomy in adults previously treated surgically for rectal cancer. Participants were assigned to either purse-string skin closure with central drainage access or linear skin closure with marginal drainage access. Both protocols included temporary passive drainage and standardized postoperative wound irrigation. The study evaluated postoperative wound healing and wound-related outcomes during 30 days of follow-up. The hypothesis was that the purse-string protocol would be associated with fewer clinically important wound complications than the linear closure protocol.
Official title: Purse-String Versus Linear Closure With Drainage Access After Diverting Ileostomy Reversal in an Exploratory Randomized Comparison of Two Wound Management Protocols
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
23
Start Date
2026-06-10
Completion Date
2026-08-10
Last Updated
2026-10-27
Healthy Volunteers
No
Conditions
Interventions
Linear Wound Management Protocol
After diverting ileostomy reversal, the skin was closed with interrupted sutures, leaving a marginal opening no greater than 5 mm for drainage and postoperative irrigation. A temporary passive rubber drain was placed through the opening and removed on postoperative day 1. The wound cavity was irrigated once daily with 20 mL of 0.05% aqueous chlorhexidine during hospitalization and for three days after discharge, followed by dry wound care.
Purse-String Wound Management Protocol
After diverting ileostomy reversal, subcutaneous tissue was approximated using absorbable sutures. The skin was closed with a circular subcuticular purse-string suture, leaving a central opening no greater than 5 mm for drainage and irrigation. A temporary passive rubber drain was placed through the opening and removed on postoperative day 1. The wound cavity was irrigated daily with 20 mL of 0.05% aqueous chlorhexidine during hospitalization and for three days after discharge, followed by dry wound care.
Locations (1)
Dnipro Regional Clinical Oncology Dispensary
Dnipro, Ukraine