Clinical Research Directory

Inclusion Criteria: * Individuals of Middle Eastern, North African, or Levantine ancestry, as determined by participant self-report. * Individuals aged 18 years or older with chronic medical conditions; a confirmed diagnosis or self-reported history of one or more chronic medical conditions, supported by medical record review where available. * Individuals below 18 years of age with a relevant chronic condition, where pediatric enrollment is subject to applicable ethical approvals and the required parental or legally authorized representative permission and participant assent, as applicable. * Healthy volunteers: Individuals aged 18 years or older without known chronic medical conditions relevant to the registry, based on participant self-report and investigator assessment. * Willing and able to provide written informed consent before initiation of any study procedures or, for pediatric participants, participation will be subject to applicable written parental/legal guardian permission and assent procedures, as appropriate. * Eligible and willing to undergo the applicable study procedures, including collection of relevant clinical information and biological samples. Exclusion Criteria: * Inability to obtain the required informed consent, parental or legally authorized representative permission, or participant assent, as applicable. * Acute illness, including fever (≥38°C), active infection, or a clinically unstable condition at the time of enrollment that, in the opinion of the investigator, may compromise participant safety or interfere with study procedures. Enrollment may be deferred until the condition resolves or the participant is clinically stable.