Clinical Research Directory
Browse clinical research sites, groups, and studies.
Comparative Study of Regional Nerve Blocks in Primary Cleft Palate Repair
Sponsor: Children's National Research Institute
Summary
This study will evaluate whether adding a suprazygomatic maxillary nerve block to the standard palatal nerve block improves pain control after cleft palate repair surgery in children. Participants will be randomly assigned to receive either the standard palatal block alone or the standard palatal block combined with a suprazygomatic maxillary nerve block. Both techniques use medications commonly used for pain management during surgery. The purpose of this study is to determine whether the addition of the suprazygomatic maxillary nerve block reduces postoperative pain, decreases the need for opioid medications, and improves recovery after cleft palate repair. Researchers will compare pain scores, medication use, recovery outcomes, and any treatment-related complications between the two groups. Information collected from this study may help identify the most effective regional anesthesia approach for children undergoing cleft palate repair and may improve postoperative pain management and patient recovery.
Key Details
Gender
All
Age Range
9 Months - Any
Study Type
INTERVENTIONAL
Enrollment
144
Start Date
2026-12-16
Completion Date
2028-12-16
Last Updated
2026-10-23
Healthy Volunteers
No
Interventions
Palatal Nerve Block
Regional anesthetic block of the palate performed during cleft palate or velopharyngeal insufficiency surgery using local anesthetic. This procedure serves as the standard pain management approach and is intended to provide perioperative analgesia and reduce postoperative pain.
Suprazygomatic Maxillary Nerve Block
Regional anesthetic block of the maxillary nerve performed via a suprazygomatic approach using local anesthetic in addition to the standard palatal nerve block. The procedure is intended to enhance perioperative analgesia, decrease postoperative pain, and reduce postoperative opioid requirements following cleft palate or velopharyngeal insufficiency surgery.