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NCT07893795

A Clinical Trial to Evaluate the Effects of the NeuEve Dryness Treatment Kit on Vaginal Health, Comfort, and Quality of Life in Postmenopausal Women

Sponsor: NeuEve

View on ClinicalTrials.gov

Summary

This is a decentralized, single-group, open-label clinical trial evaluating a 12-week regimen of the NeuEve Dryness Treatment Kit (comprising Feminine Moisture Support oral softgels, Bone Support oral capsules, NeuEve Salve vulvar topical cream, NeuEve vaginal suppositories, and NeuEve Multivitamin) in postmenopausal women aged 55-65 who experience vaginal dryness, painful sex, and vaginal itching. The study aims to evaluate the effect of the kit on vaginal symptoms, vaginal pH, vaginal microbiome composition, sexual function, and quality of life over 12 weeks of use.

Key Details

Gender

FEMALE

Age Range

55 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

Start Date

2026-09

Completion Date

2026-12

Last Updated

2026-10-26

Healthy Volunteers

Yes

Conditions

Relieves Vaginal Dryness / Improves Self-Lubrication Improves Strength & Elasticity of Vagina (Aka Collagen and Elastin)Improves Vaginal Wall Thickness Reduces Pain During Sex Reduces Vaginal Odor Improves Vaginal Microbiome i.e. Increases Lactobacilli Reduces Vaginal Itching, Improves Vaginal Burning & Discharge Lowers Vaginal pH to 3.8-4.5 Improves Libido / Sexual Desire Improves Orgasm / Sexual Satisfaction

Interventions

DIETARY_SUPPLEMENT

Intervention

All participants receive the five-component NeuEve Dryness Treatment Kit for 12 weeks: Feminine Moisture Support (1 softgel orally twice daily with meals); Bone Support (1 capsule orally twice daily with meals); NeuEve Salve (dime-sized amount applied topically to the vulva once daily at bedtime); NeuEve Silk Suppository (1 suppository inserted vaginally every other day at bedtime for Weeks 1-4) transitioning to NeuEve Silver Suppository (1 suppository inserted vaginally every 5 days for Weeks 5-12); and NeuEve Multivitamin (3 capsules daily with food, divided equally across the day).

Exclusion Criteria: Female, aged 55-65 years at the time of consent. Postmenopausal (defined as ≥12 consecutive months without menstrual bleeding, or surgical menopause). Currently experiencing self-reported vaginal dryness, painful sex (dyspareunia), and vaginal itching. Willing and able to use all five products of the NeuEve Dryness Treatment Kit as directed for 12 weeks. Willing to perform at-home vaginal pH testing and at-home vaginal microbiome sample collection. Willing to maintain current diet, sleep schedule, and physical activity level for the duration of the 12-week study. Willing to complete all study questionnaires via the Citruslabs platform. Resides in the United States with a deliverable shipping address. Exclusion criteria: Known allergy or hypersensitivity to any ingredient in any component of the NeuEve Dryness Treatment Kit (including palm/coconut oil, beeswax, sea buckthorn, evening primrose, botanical extracts, or essential oils listed in the formulations). Currently pregnant, breastfeeding, or planning pregnancy during the study period. Self-reported diagnosed with or treated for a sexually transmitted infection (STI), pelvic inflammatory disease (PID), or a vaginal or urinary tract infection within the past 30 days. Current use of systemic or vaginal estrogen therapy, vaginal DHEA, or any other prescription treatment for vaginal dryness/GSM, unless on a stable regimen for ≥3 months and willing to maintain it without changes during the study (use of competing topical/vaginal moisturizers, lubricants, or suppositories during the study period is not permitted). History of gynecologic cancer (cervical, vaginal, vulvar, endometrial, or ovarian) within the past 2 years, or current active malignancy. Current participation in another interventional clinical study. Any medical condition that, in the opinion of the investigator, would compromise participant safety or the integrity of the study data. Planning to travel outside of the United States during the study duration.

Locations (1)

Citruslabs

Las Vegas, Nevada, United States