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RECRUITING
NCT07894016
PHASE4

Comparison of Amoxicillin, Clindamycin and Azithromycin Single Doses Antibiotic Prophylaxis in Patient Undergoing Lower Third Molar Extraction

Sponsor: Dow University of Health Sciences

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn which drug amongst Amoxicillin, Clindamycin and Azithromycin single dose works better in reducing post-surgical complications in Participants getting lower wisdom teeth pulled. The main question it aims to answer is: • Which single dose drug lowers the post-surgical complications in participants of this study? Researcher will compare three single dose drugs (the administration of the complete amount of an antibiotic medication in one single administration to cure or prevent an infection). Participants will: * Take provided drug one hour before the treatment * Visit the OPD for Reading measurements same day before the surgery, same day after the surgery and third day after the surgery.

Official title: Comparison of Amoxicillin, Clindamycin and Azithromycin Single Doses Antibiotic Prophylaxis in Patient Undergoing Lower Third Molar Extraction, A Randomized Control Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

105

Start Date

2026-10-20

Completion Date

2026-12-30

Last Updated

2026-11-02

Healthy Volunteers

No

Interventions

DRUG

Amoxicillin 2g

single dose

DRUG

Clindamycin 600 mg

Single dose

DRUG

Azithromycin 500mg

Single dose

Locations (1)

Dr. Ishrat-ul-Ebad Khan Institute of Oral Health Sciences

Karachi, Sindh, Pakistan