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COMPLETED
NCT07894848
NA

Sutureless Suerior vs Inferior Conjunctival Autograft for Pterygium

Sponsor: Fayoum University

View on ClinicalTrials.gov

Summary

Superior bulbar conjunctival autograft is the standard procedure to reduce recurrence after pterygium excision. However, harvesting superior conjunctiva causes tissue scarring, which may compromise the site for potential future glaucoma filtering surgeries. This study evaluates whether harvesting a sutureless autograft from the inferior bulbar/forniceal conjunctiva provides comparable graft stability, pain levels, and recurrence rates while preserving the superior conjunctiva.

Official title: Comparison Between Sutureless Superior and Inferior Conjunctival Autograft in Treatment of Pterygium.

Key Details

Gender

All

Age Range

30 Years - Any

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2025-04-27

Completion Date

2026-03-02

Last Updated

2026-10-26

Healthy Volunteers

No

Interventions

OTHER

Sutureless Superior Conjunctival Autograft (CAG)

Following local anesthesia with topical proparacaine 0.5% and subconjunctival 2% lidocaine infiltration, standard surgical excision of the primary pterygium head and body is performed along with meticulous clearance of corneal and scleral bed fibrovascular tissue. A thin, donor conjunctival autograft matching the dimensions of the bare scleral bed (measured via surgical calipers) is harvested from the superior limbal/bulbar conjunctiva, incorporating limbal stem cell tissue. The graft is transferred to the recipient site maintaining correct orientation (limbus-to-limbus). Fixation is achieved suturelessly without the use of synthetic sutures. Pressure is applied over the graft for 5 to 10 minutes to ensure firm apposition prior to monocular eye patching.

OTHER

Sutureless Inferior Conjunctival Autograft (CAG)

Following local anesthesia with topical proparacaine 0.5% and subconjunctival 2% lidocaine infiltration, standard surgical excision of the primary pterygium head and body is performed along with meticulous clearance of corneal and scleral bed fibrovascular tissue. A thin, donor conjunctival autograft matching the dimensions of the bare scleral bed (measured via surgical calipers) is harvested from the infronasal / inferior bulbar and forniceal conjunctiva, deliberately sparing the entire superior bulbar conjunctiva for potential future ocular surgeries. The graft is transferred to the recipient site maintaining correct limbus-to-limbus orientation. Fixation is achieved suturelessly without the use of synthetic sutures. Pressure is applied over the graft for 5 to 10 minutes to ensure firm apposition prior to monocular eye patching.

Locations (1)

Fayoum university Hospital

Al Fayyum, Faiyum Governorate, Egypt