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Comparing Intravitreal Injection Pain Scores Using Iheezo (Chloroprocaine Hcl Ophthalmic Gel 3%) Versus Subconjunctival Lidocaine (2%): A Randomized, Controlled Trial
Sponsor: Retina Research Institute, LLC
Summary
This will be a prospective, randomized, controlled non-inferiority trial comparing the efficacy of Iheezo versus subconjunctival 2% lidocaine in reducing intravitreal injection pain scores up to 24 hours after injection.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2025-10-30
Completion Date
2026-12-30
Last Updated
2026-10-26
Healthy Volunteers
No
Conditions
Interventions
chloroprocaine HCL 3%
Topical anesthetic for intravitreal injection
Subconjunctival Lidocaine
Procedural anesthetic for intravitreal injection
Locations (4)
The Retina Institute
Glen Carbon, Illinois, United States
The Retina Institute
Chesterfield, Missouri, United States
The Retina Institute
City of Saint Peters, Missouri, United States
The Retina Institute
St Louis, Missouri, United States