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Multimodal Monitoring During General Anesthesia in ENT Surgery
Sponsor: Barbara Verro
Summary
This study evaluated whether using several monitoring methods together during general anesthesia could improve patient safety and help anesthesiologists adjust medication doses in adults undergoing ear, nose, and throat (ENT) surgery. The study included 200 adult patients at a university hospital in Palermo, Italy. Patients were assigned alternately to one of two groups. One group received standard monitoring together with additional monitoring of anesthesia depth (BIS), responses to surgical stimulation (SPI), and muscle relaxation (TOF). The other group received standard monitoring alone. Group assignment followed a fixed alternating sequence rather than random selection. The researchers compared the amount of anesthetic medication used during surgery and the occurrence of anesthesia-related complications during the first 48 hours after surgery, including delayed recovery of breathing, nausea and vomiting, shivering, and residual muscle weakness. The study was conducted between February and December 2025 and has been completed.
Official title: Continuous Multiparametric Monitoring During General Anesthesia in ENT Surgery
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2025-02-28
Completion Date
2025-12-31
Last Updated
2026-10-27
Healthy Volunteers
No
Conditions
Interventions
Multimodal Anesthesia Monitoring (BIS, SPI, TOF)
Integrated intraoperative monitoring using the Bispectral Index (BIS) to assess anesthetic depth, the Surgical Pleth Index (SPI) to assess nociceptive responses, and quantitative train-of-four (TOF) monitoring to assess neuromuscular blockade. Monitoring information was used to support individualized adjustment of anesthetic, analgesic, and neuromuscular blocking agents during general anesthesia.
Standard Anesthesia Monitoring
Standard intraoperative anesthesia monitoring according to routine clinical practice during ear, nose, and throat surgery, without the additional integrated BIS, SPI, and quantitative TOF-guided monitoring strategy.
Locations (1)
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone
Palermo, Palermo, Italy