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The Efficacy of Exosomes Combined With Synthetic Bone Graft for the Treatment of Periodontal Intra-bony Defects
Sponsor: Khoshoe Al-mokhtar Mohammed
Summary
The aim of this study will be to evaluate clinically, radiographically and biochemically the efficacy of exosomes combined with synthetic bone graft for the treatment of periodontal intra-bony defects.
Official title: The Efficacy of Exosomes Combined With Synthetic Bone Graft in Treatment of Periodontal Intra-Bony Defects in Periodontitis Patients (A Comparative Clinical, Radiographic and Biochemical Study)
Key Details
Gender
All
Age Range
16 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-10-25
Completion Date
2027-11
Last Updated
2026-10-27
Healthy Volunteers
Yes
Interventions
single flap approach
Periodontitis patients with an intra-bony defect will be treated by single flap approach only
single flap approach combined with nanocrystalline hydroxyapatite bone substitute
single flap approach combined with nanocrystalline hydroxyapatite bone substitute
Exosomes
Periodontitis patients with an intra-bony defect will be treated by single flap approach combined with exosome and nanocrystalline hydroxyapatite bone substitute
Locations (2)
Faculty of Dental Medicine, Al-Azhar University (Assiut branch)
Asyut, Egypt
Faculty of Dentistry, Assiut University
Asyut, Egypt