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Cardiac Arrest - Ultrasound Detection of Occult Perfusion
Sponsor: University of Massachusetts, Worcester
Summary
The goal of this study is to describe the population of patients presenting after out of hospital cardiac arrest with occult perfusion, defined as a patient without a palpable pulse but with some evidence of pulsatile arterial flow. The main questions it aims to answer are: * To measure the prevalence of patients of patients presenting to the emergency department after out of hospital cardiac arrest with occult perfusion * To measure the association between occult perfusion and survival * Compare survival between patients with occult perfusion that were treated as pulseless by ACLS interventions vs those treated as hypotensive Researchers will describe the percentage of out-of-hospital cardiac arrest presenting to the emergency department without a pulse but with occult perfusion. Researchers will also compare survival endpoints (ROSC, Survival to hospital Admission, and Survival to Hospital Discharge) in pulseless patients with occult perfusion treated with ACLS interventions only and pulseless patients with occult perfusion treated as if they had pulsatile arterial flow. Participants will undergo resuscitation based on decisions by the clinical team who incorporate echo and/or vascular ultrasound during the first three rounds of CPR. The resuscitation will continue until the patient demonstrates return of spontaneous circulation or until the clinical team halts resuscitative efforts due to futility.
Official title: Bedside Ultrasound Detection of Occult Prefusion in the Emergency Department Following Out-of-Hospital Cardiac Arrest.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1400
Start Date
2026-10-01
Completion Date
2029-10-01
Last Updated
2026-10-27
Healthy Volunteers
No
Locations (8)
Denver Health
Denver, Colorado, United States
UmassMemorial Medical Center
Worcester, Massachusetts, United States
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States
St Barnabas Hospital
New York, New York, United States
UH Cleveland Medical Center
Cleveland, Ohio, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
VCU Health
Richmond, Virginia, United States
University of Washington
Seattle, Washington, United States