Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT07897370

Cardiac Arrest - Ultrasound Detection of Occult Perfusion

Sponsor: University of Massachusetts, Worcester

View on ClinicalTrials.gov

Summary

The goal of this study is to describe the population of patients presenting after out of hospital cardiac arrest with occult perfusion, defined as a patient without a palpable pulse but with some evidence of pulsatile arterial flow. The main questions it aims to answer are: * To measure the prevalence of patients of patients presenting to the emergency department after out of hospital cardiac arrest with occult perfusion * To measure the association between occult perfusion and survival * Compare survival between patients with occult perfusion that were treated as pulseless by ACLS interventions vs those treated as hypotensive Researchers will describe the percentage of out-of-hospital cardiac arrest presenting to the emergency department without a pulse but with occult perfusion. Researchers will also compare survival endpoints (ROSC, Survival to hospital Admission, and Survival to Hospital Discharge) in pulseless patients with occult perfusion treated with ACLS interventions only and pulseless patients with occult perfusion treated as if they had pulsatile arterial flow. Participants will undergo resuscitation based on decisions by the clinical team who incorporate echo and/or vascular ultrasound during the first three rounds of CPR. The resuscitation will continue until the patient demonstrates return of spontaneous circulation or until the clinical team halts resuscitative efforts due to futility.

Official title: Bedside Ultrasound Detection of Occult Prefusion in the Emergency Department Following Out-of-Hospital Cardiac Arrest.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1400

Start Date

2026-10-01

Completion Date

2029-10-01

Last Updated

2026-10-27

Healthy Volunteers

No

Locations (8)

Denver Health

Denver, Colorado, United States

UmassMemorial Medical Center

Worcester, Massachusetts, United States

Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, United States

St Barnabas Hospital

New York, New York, United States

UH Cleveland Medical Center

Cleveland, Ohio, United States

Vanderbilt University Medical Center

Nashville, Tennessee, United States

VCU Health

Richmond, Virginia, United States

University of Washington

Seattle, Washington, United States