Clinical Research Directory

Inclusion Criteria: * Be male or female. * Be aged 18-65. * BMI ≥ 27. * Anyone currently taking a GLP-1-based therapy, including GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists. * Anyone experiencing issues regarding at least two of the following symptoms since starting a GLP-1 receptor agonist medication, at a frequency of at least 2-3 times per week: gut discomfort, diarrhea, abdominal pain/cramping, bloating, or nausea. * Self-reported low fruit and vegetable intake (less than 2 pieces per day). * Anyone who is generally healthy - does not live with any uncontrolled chronic disease. * If taking oral over-the-counter supplements or herbal remedies targeted at gut comfort, has been consistently taking these for at least 3 months prior to starting the study, and is willing to maintain this routine for the study duration. * Resides in the United States. * Anyone who is willing to follow the study protocol. * Anyone willing to maintain their current diet, sleep pattern, and activity levels for the duration of the trial. Exclusion Criteria: * Anyone with chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders. * Use of antibiotics in the last 15 days. * Anyone planning on introducing any products or any new forms of prescription medication or supplements that target gut comfort for the study duration. * Anyone with a known history of severe digestive disorders like acid reflux, celiac disease, Irritable Bowel Syndrome (IBS), Irritable Bowel Disease (IBD), ulcerative colitis, Crohn's disease, or gastrointestinal tract surgeries. * Anyone with any allergies or sensitivities to any of the study product ingredients. * Any women who are pregnant, breastfeeding, or trying to conceive (or who will be at any point during the study period). * Anyone taking anticoagulants ('blood thinners') or who has been diagnosed with a bleeding disorder. * Anyone who takes medications that may interact with botanical supplements, including but not limited to antihypertensives, blood glucose-lowering agents, anticoagulants/antiplatelet therapies, or medications known to interact with grapefruit. * Anyone who has a history of serious illness in the last three months. * Anyone who has planned surgery during the study period. * Anyone with a history of substance abuse. * Anyone who is a heavy drinker (i.e., a woman who drinks eight or more alcoholic drinks per week or a man who drinks 15 or more alcoholic drinks per week). * Anyone who is currently a smoker or has been a smoker in the past 3 months. * Currently partaking in another research study or will be partaking in any other research study at any point during this study's duration. * Anyone with a chronic hepatic or renal disease. * Anyone with a known sulphite sensitivity.