Clinical Research Directory

Inclusion Criteria: * Age ≥18 years. * Diagnosis of obstructive sleep apnea with an apnea-hypopnea index (AHI) ≥15 events/hour, confirmed by attended in-laboratory polysomnography (PSG) before enrollment and implantation. * Complete concentric collapse (CCC) of the soft palate on clinically obtained drug-induced sleep endoscopy (DISE). * Otherwise considered an appropriate candidate for HGNS implantation by the treating surgical and sleep medicine team, aside from CCC status. * Prior CPAP failure or intolerance, consistent with usual HGNS candidacy evaluation. * Ability to provide informed consent. * Willingness to undergo investigational HGNS implantation and required follow-up procedures under the research protocol. Exclusion Criteria: * Contraindications to HGNS implantation or conditions that, in the judgment of the treating clinicians or investigators, make investigational HGNS use unsafe or inappropriate. * Central or mixed sleep apnea comprising \>25% of total respiratory events. * Any unstable or uncontrolled medical condition that, in the judgment of the investigator, would increase procedural risk or interfere with study participation. * Inability to safely undergo study procedures, including overnight sleep studies or physiological monitoring. * Prior HGNS implantation. * Pregnancy