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NOT YET RECRUITING
NCT07898826
NA

Functional Regulation of Autoreactive Lymphocytes: Phenotypic and Transcriptomic Investigations in Healthy Subjects

Sponsor: University Hospital, Brest

View on ClinicalTrials.gov

Summary

The goal of this study is to study the autoreactive lymphocytes in healthy volunteers. More specifically, this research aims to identify what distinguishes the autoreactive lymphocytes found in healthy individuals from those observed in patients, and to understand the mechanisms that prevent the onset of autoimmune disease in healthy individuals. Participants will have a single visit where they will undergo a blood drawing (56mL). Some participants will be proposed to join a longitudinal cohort consisting in two supplementary visits at M12 and M24 where they will undergo a new blood drawing (56mL).

Key Details

Gender

All

Age Range

18 Years - 69 Years

Study Type

INTERVENTIONAL

Enrollment

300

Start Date

2026-11-01

Completion Date

2031-11-01

Last Updated

2026-10-27

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Blood sampling at D0

Blood sampling (56mL)

DIAGNOSTIC_TEST

Blood sampling at D0, M12 and M24

Blood sampling (56mL)

Locations (1)

Centre Hospitalier Universitaire de Brest

Brest, France