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Farm-originated Antimicrobial Resistance Modeling: Exploring Humans-to-Animal Dissemination
Sponsor: Centre Hospitalier de Saint-Brieuc
Summary
Antimicrobial resistance is a major public health issue. Methicillin resistance in Staphylococcus aureus (MRSA) is one of the indicators that is monitored particularly closely. In animals, pig farms, among others, have been identified as reservoirs of MRSA, with a risk of transmission to humans, particularly to individuals in direct contact with livestock. In France, the prevalence of MRSA in pig farms has increased markedly in recent years. While cross-species transmission between pigs and humans in professional settings is well-documented, the temporal dynamics, the actual incidence of acquisition, and the associated determinants remain insufficiently characterized in France. Adopting a "One Health" approach, this project aims to gain a better understanding of the mechanisms by which MRSA spreads between animal and human subpopulations and to incorporate these insights into a mathematical modeling framework.
Official title: Farm-originated Antimicrobial Resistance Modeling: Exploring Humans-to-Animal Dissemination - FARMHAND
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-11
Completion Date
2028-11
Last Updated
2026-10-27
Healthy Volunteers
Yes
Interventions
Sample collection
Participants will be asked to provide two types of samples, only one of which will contain personally identifiable information. * Nasal samples: a monthly self-collected nasal swab, performed at approximately the same time each month. * Dust samples: following the collection and storage of the nasal swab, participants will be asked to collect dust samples from the production area-specifically, from the room within the fattening facility that houses the oldest animals-by wiping surfaces using a small cloth.
Locations (2)
Anses Ploufragan - Plouzané - Niort, site de Ploufragan
Ploufragan, France
Centre Hospitalier de Saint-Brieuc - Paimpol - Tréguier, site de Saint-Brieuc
Saint-Brieuc, France