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COMPARISON OF THE POSTOPERATIVE ANALGESIC EFFECTS OF ULTRASOUND-GUIDED QUADRO-ILIAC PLANE AND TRANSVERSUS ABDOMINIS PLANE BLOCKS IN PATIENTS UNDERGOING TOTAL LAPAROSCOPIC HYSTERECTOMY
Sponsor: Hitit University
Summary
Postoperative pain management is an important component of recovery after total laparoscopic hysterectomy. Regional anesthesia techniques may reduce postoperative opioid consumption and improve patient comfort. This prospective, randomized, double-blind clinical trial aims to compare the postoperative analgesic efficacy of ultrasound-guided bilateral Quadro-Iliac Plane Block (QIPB) and bilateral Transversus Abdominis Plane Block (TAPB) in patients undergoing total laparoscopic hysterectomy. A total of 60 patients will be randomly assigned to two groups, with 30 patients in each group. One group will receive bilateral QIPB, while the other group will receive bilateral TAPB before surgery. The primary outcome will be total opioid consumption during the first 24 postoperative hours. Secondary outcomes will include postoperative pain scores, sensory block assessment, postoperative nausea and vomiting, quality of recovery, and time to first mobilization. The study aims to determine the comparative analgesic effectiveness of these two regional anesthesia techniques and contribute to optimizing postoperative pain management after total laparoscopic hysterectomy.
Official title: COMPARISON OF THE POSTOPERATIVE ANALGESIC EFFICACY OF ULTRASOUND-GUIDED QUADRO-ILIAC PLANE BLOCK AND TRANSVERSUS ABDOMINIS PLANE BLOCK IN PATIENTS SCHEDULED FOR TOTAL LAPAROSCOPIC HYSTERECTOMY
Key Details
Gender
FEMALE
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-12
Completion Date
2027-06
Last Updated
2026-10-27
Healthy Volunteers
No
Interventions
Ultrasound-Guided Bilateral Quadro-Iliac Plane Block
Patients allocated to Group Q will receive ultrasound-guided bilateral Quadro-Iliac Plane Block (QIPB) before total laparoscopic hysterectomy. The regional block will be performed by an experienced anesthesiologist using ultrasound guidance and local anesthetic administration according to the approved study protocol. All patients will receive standardized general anesthesia and postoperative multimodal analgesia.
Ultrasound-Guided Bilateral Transversus Abdominis Plane Block
Patients allocated to Group T (n=30) will receive ultrasound-guided bilateral Transversus Abdominis Plane Block (TAPB) before total laparoscopic hysterectomy. Local anesthetic will be administered into the fascial plane between the internal oblique and transversus abdominis muscles under ultrasound guidance. All patients will receive standardized general anesthesia and postoperative multimodal analgesia.