Clinical Research Directory

Inclusion Criteria: * Patients with unilateral severe carpal tunnel syndrome confirmed by clinical and electrophysiological assessment. * Presence of thenar muscle atrophy on clinical examination. * Patients who have undergone carpal tunnel release surgery for the affected hand. * Medically cleared by the treating surgeon to participate in postoperative hand rehabilitation. * Adequate wound healing allowing initiation of the prescribed rehabilitation program. * Ability to understand and follow verbal and written instructions. * Ability to perform the required hand and thumb movements safely. * Willingness to participate in the complete rehabilitation program and outcome assessments. * Provision of written informed consent. Exclusion Criteria: * Previous surgery or major trauma involving the affected wrist or hand. * Other peripheral neuropathies affecting the upper limb or hand. * Cervical radiculopathy, cervical myelopathy, or other neurological disorders that may affect hand function. * Coexisting neurological disorders affecting upper-limb motor function. * Musculoskeletal conditions of the shoulder, elbow, wrist, or hand that significantly limit hand function or interfere with the intervention. * Bilateral carpal tunnel syndrome requiring simultaneous rehabilitation of both hands. * Previous carpal tunnel release surgery on the same hand. * Postoperative complications that prevent or substantially limit participation in rehabilitation. * Severe cognitive, visual, or communication impairment that prevents understanding or performing the intervention.