Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT07900022
NA

Ozonated Olive Oil for Mini-Screw Complications in Molar Intrusion

Sponsor: Yuzuncu Yil University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial was to learn whether ozonated olive oil can reduce complications around orthodontic mini-screws in patients with anterior open bite who receive maxillary molar intrusion as part of fixed orthodontic treatment. The study also compared ozonated olive oil with chlorhexidine, the antiseptic most commonly used for this purpose. The main questions it aimed to answer were: * Does ozonated olive oil reduce bleeding, plaque accumulation and mobility around mini-screws compared with chlorhexidine? * Does ozonated olive oil affect pocket depth, bleeding, plaque and mobility of the teeth next to the mini-screws? * Is pain after mini-screw placement different between the two products? Each participant received four mini-screws (two buccal, two palatal) in the upper jaw. One side of the mouth was treated with ozonated olive oil spray and the other side with chlorhexidine spray (split-mouth design), and the side for each product was chosen randomly. Participants: * Applied 10 sprays per day of each assigned product to its side for 7 days after mini-screw placement * Attended measurements before treatment, on the day of placement, and on days 7, 14 and 21 * Rated their pain on a visual analog scale at set time points after placement

Official title: Effect of Ozonated Olive Oil on Mini-Screw Complications During Orthodontic Treatment Combined With Molar Intrusion

Key Details

Gender

All

Age Range

12 Years - 24 Years

Study Type

INTERVENTIONAL

Enrollment

26

Start Date

2021-12-20

Completion Date

2022-04-25

Last Updated

2026-10-28

Healthy Volunteers

No

Interventions

OTHER

Ozonated Olive Oil

Ozonated olive oil oral spray (50 mL) applied to the mini-screw sites on the assigned side, 10 sprays per day for 7 days after mini-screw placement.

OTHER

Chlorhexidine

0.2% chlorhexidine gluconate oral spray (Kloroben) applied to the mini-screw sites and adjacent teeth on the contralateral side of the maxilla, 10 sprays per day for 7 days after mini-screw placement. Serves as the active comparator in this split-mouth design.

Locations (2)

Van Yuzuncu Yil University, Faculty of Dentistry

Van, Van, Turkey (Türkiye)

Van Yuzuncu Yil University, Faculty of Dentistry

Van, Van, Turkey (Türkiye)