Clinical Research Directory

Low-Dose Linperlisib Achieves Rapid Hematological Response in a Patient With Pure Red Cell Aplasia and Moderate-to-Severe Renal Insufficiency: A Case Report

Sponsor: Peking Union Medical College Hospital

Summary

This article reports a case of a 70-year-old male patient diagnosed with T-cell large granular lymphocytic leukemia (T-LGLL)-associated pure red cell aplasia (PRCA) complicated by moderate-to-severe renal insufficiency. The patient was refractory or intolerant to multiple prior treatment lines, including cyclosporine A, tacrolimus plus prednisone, sirolimus, and cyclophosphamide, and was transfusion-dependent. In this case,we choose the low-dose linperlisib.

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