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Clinical Efficacy of a Natural Biopolymer-Based Irrigant
Sponsor: Minia University
Summary
One primary objective in the root canal treatments is to ensure chemo mechanical removal of microorganisms and organic/inorganic tissue residues from the infected root canals. Studies in the literature report that due to the structure of the root canals, mechanical instrumentation alone could not perform a satisfying cleaning in the canal. some areas have remained unreached and infected, thus irrigation has played a key role in the achievement of root canal treatments.
Official title: Clinical Efficacy of a Natural Biopolymer-Based Irrigant Under Apical Negative Pressure on Postoperative Sequelae: A Randomized Controlled Clinical Trial
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
84
Start Date
2026-01-05
Completion Date
2027-01-05
Last Updated
2026-10-28
Healthy Volunteers
No
Conditions
Interventions
Chitosan Nanoparticles
To evaluate the incidence and intensity of postoperative pain and acute exacerbations following root canal debridement using Apical Negative Pressure-mediated Chitosan nanoparticles versus Sodium Hypochlorite.
Locations (1)
Endodontics Department Faculty of Dentistry
Minya, Egypt