Clinical Research Directory
Browse clinical research sites, groups, and studies.
KLF4 Epigenetic Modulation
Sponsor: Azienda USL Reggio Emilia - IRCCS
Summary
The study investigates the epigenetic regulation of KLF4 during the progression from colorectal polyps to adenomas and carcinomas. Quantitative KLF4 methylation will be assessed in colorectal tissue samples obtained during routine colonoscopy, together with KLF4 gene expression and its correlation with methylation status in matched tissue samples. The study will also evaluate quantitative and site-specific molecular approaches for the assessment of KLF4 methylation.
Official title: KLF4 Epigenetic Modulation During Polyps-adenoma Progression
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
170
Start Date
2026-10
Completion Date
2028-07
Last Updated
2026-10-28
Healthy Volunteers
No
Conditions
Locations (1)
Azienda USL IRCCS di Reggio Emilia
Reggio Emilia, Italy