Clinical Research Directory

Inclusion Criteria: * Age 18 years or older. * Admission to University Hospital with moderate-to-severe TBI from any injury mechanism. * Moderate-to-severe TBI defined by GCS 3-12 * Enrollment within 24 hours of presentation to UH * Informed consent from the participant or an authorized surrogate through the approved consent process. Exclusion Criteria: * Age younger than 18 years, because this study is limited to adults. * Injury that does not meet the study's definition of moderate-to-severe TBI. * Presentation outside the approved enrollment window. * Inability to obtain participant or authorized surrogate consent within the enrollment window.