Clinical Research Directory

Inclusion Criteria: * Female with age ranging from 20-40 years. * Suffering from unilateral or bilateral signs and symptoms of myofascial pain dysfunction (MPD), selected patients were systemically free with no chronic diseases. Exclusion Criteria: * Patients with history of Malignancy or a history of previous surgery of neck and/or shoulder within the past year of the study. * Any patient had treatment that can affect the muscles will be excluded, either pharmacological treatment (e.g., opioids, morphine, muscle relaxants or anti-depressants), physiotherapy management or occlusal appliances. * Patients with pain of dental etiology. * Pregnant and lactating women and patients with history of allergy or coagulation disorders.