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Lymph Node Dissection After Neoadjuvant Therapy for Gastric and EGJ Adenocarcinoma
Sponsor: The First Affiliated Hospital with Nanjing Medical University
Summary
This multicenter retrospective observational cohort study will evaluate approximately 2,000 adults with gastric or esophagogastric junction adenocarcinoma who received at least two cycles of neoadjuvant therapy followed by R0 gastrectomy with lymph node dissection. The study will estimate the frequency of pathological metastasis at individual lymph node stations according to the final preoperative imaging-based ycT and ycN categories and tumor location. The findings are intended to provide evidence for future prospective studies of risk-adapted reduction of perigastric lymph node dissection. No treatment is assigned by this study.
Official title: Optimizing the Extent of Lymph Node Dissection After Neoadjuvant Therapy for Gastric and Esophagogastric Junction Adenocarcinoma: A Multicenter Retrospective Cohort Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2000
Start Date
2026-10-25
Completion Date
2027-02-27
Last Updated
2026-10-29
Healthy Volunteers
No
Locations (8)
The Fourth Hospital of Hebei Medical University
Shijiazhuang, Hebei, China
The First People's Hospital of Lianyungang
Lianyungang, Jiangsu, China
Affiliated Drum Tower Hospital, Medical School of Nanjing University
Nanjing, Jiangsu, China
Jiangsu Cancer Hospital
Nanjing, Jiangsu, China
The First Affiliated Hospital with Nanjing Medical University
Nanjing, Jiangsu, China
The First Affiliated Hospital of Soochow University
Suzhou, Jiangsu, China
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, China