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NOT YET RECRUITING
NCT07902596

Lymph Node Dissection After Neoadjuvant Therapy for Gastric and EGJ Adenocarcinoma

Sponsor: The First Affiliated Hospital with Nanjing Medical University

View on ClinicalTrials.gov

Summary

This multicenter retrospective observational cohort study will evaluate approximately 2,000 adults with gastric or esophagogastric junction adenocarcinoma who received at least two cycles of neoadjuvant therapy followed by R0 gastrectomy with lymph node dissection. The study will estimate the frequency of pathological metastasis at individual lymph node stations according to the final preoperative imaging-based ycT and ycN categories and tumor location. The findings are intended to provide evidence for future prospective studies of risk-adapted reduction of perigastric lymph node dissection. No treatment is assigned by this study.

Official title: Optimizing the Extent of Lymph Node Dissection After Neoadjuvant Therapy for Gastric and Esophagogastric Junction Adenocarcinoma: A Multicenter Retrospective Cohort Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

2000

Start Date

2026-10-25

Completion Date

2027-02-27

Last Updated

2026-10-29

Healthy Volunteers

No

Locations (8)

The Fourth Hospital of Hebei Medical University

Shijiazhuang, Hebei, China

The First People's Hospital of Lianyungang

Lianyungang, Jiangsu, China

Affiliated Drum Tower Hospital, Medical School of Nanjing University

Nanjing, Jiangsu, China

Jiangsu Cancer Hospital

Nanjing, Jiangsu, China

The First Affiliated Hospital with Nanjing Medical University

Nanjing, Jiangsu, China

The First Affiliated Hospital of Soochow University

Suzhou, Jiangsu, China

The Affiliated Hospital of Qingdao University

Qingdao, Shandong, China

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China