Clinical Research Directory

Inclusion Criteria:Age ≥18 years Symptomatic atrial fibrillation Failure, intolerance or contraindication of at least one class I or III antiarrhythmic drug Suitable candidate for intracardiac mapping and ablation Willing to attend follow-up for at least 12 months Signed informed consent - Exclusion Criteria:Continuous AF \>36 months AF due to electrolyte imbalance, thyroid disease or other reversible/non-cardiac cause Rheumatic heart disease; severe mitral regurgitation; hypertrophic cardiomyopathy LA diameter \>60 mm; LVEF \<35 %; NYHA class III-IV or uncontrolled heart failure BMI \>42 kg/m² Prior LA ablation, septal closure device or mitral valve surgery Intracardiac thrombus, tumor or abnormality precluding catheter access Coagulopathy or bleeding diathesis Active infection, sepsis or fever \>38 °C within one week before ablation Significant restrictive or obstructive pulmonary disease Dialysis or renal impairment deemed prohibitive by the investigator Allergy/intolerance to anticoagulation, antiplatelet therapy or contrast Pregnancy or breastfeeding Participation in a concurrent study affecting results Life expectancy \<12 months or other condition deemed prohibitive by the investigator \-