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Diagnostic Value of Oropharyngeal Suction and Effect of Respiratory Physiotherapy on the Detection of Microorganisms in the Pediatric Patient
Sponsor: Corporacion Parc Tauli
Summary
The goal of this clinical trial is to determine the effectiveness of oropharyngeal suction in detecting microorganisms by comparing it with induced sputum and oropharyngeal swab samples. It also aims to assess the effect of respiratory physiotherapy on improving the results obtained in children aged 5-18 years with chronic lung disease. The main questions it aims to answer are: * What is the diagnostic efficacy of oropharyngeal suction in detecting microorganisms compared with induced sputum? * What is the effect of undergoing a physiotherapy session before sample collection? * How do the results obtained from oropharyngeal suction correlate with those obtained from oropharyngeal swabs? * How does the age of the participants affect the results obtained from each sampling technique and the effect of prior physiotherapy? * Are these techniques safe? Researchers will compare samples collected after a physiotherapy session with those collected without prior physiotherapy to determine whether physiotherapy improves culture results. Participants will be randomized into two groups: one group will undergo a physiotherapy session before sample collection, while the other will not. Three samples will be collected from each participant using oropharyngeal suction, an oropharyngeal swab, and induced sputum. Each participant may take part on multiple occasions, provided that at least one month has elapsed since their previous participation. On each occasion, participants will be randomized again.
Official title: Diagnostic Value of Oropharyngeal Suction Compared With Induced Sputum and Oropharyngeal Swab, and the Effect of Respiratory Physiotherapy on the Detection of Microorganisms in Paediatric Patients With Chronic Respiratory Disease: a Randomized Clinical Trial
Key Details
Gender
All
Age Range
5 Years - 18 Years
Study Type
INTERVENTIONAL
Enrollment
196
Start Date
2026-06-01
Completion Date
2028-06
Last Updated
2026-10-29
Healthy Volunteers
No
Interventions
Respiratory physiothperapy
It has not been studied whether carrying out a respiratory physiotherapy session prior to sampling improves the diagnostic performance of the different methods.
Oropharyngeal suction
Sterile aspiration of the oropharyngeal area to collect mucus.
Oropharyngeal swab
Sterile swab of the oropharyngeal area to collect mucus.
Induced Sputum
Collection of expectorated sputum after a 15-minute nebulization with a 4.5% hypertonic saline solution
Locations (1)
Corporació Sanitària Parc Taulí
Sabadell, Barcelona, Spain