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Povidone-Iodine and Ozonated Distilled Water Irrigation in the Management of Maxillofacial Space Infections
Sponsor: Alexandria University
Summary
Maxillofacial space infections are among the most common infections encountered in oral and maxillofacial surgery and may progress to severe, life-threatening complications if not properly managed, making their treatment a critical component of maxillofacial surgical practice(1).In recent years, Ozonated distilled water has emerged as a promising alternative owing to its potent antimicrobial activity against bacteria, viruses, and fungi, while demonstrating minimal toxicity to host tissues.(2-3) Aim: thus, the aim of the present study is to investigate whether ozonated distilled water irrigation in patients experiencing facial space infection after surgical incision and drainage of the maxillofacial space infection would result in resolution of infection, reduction of postoperative pain and reduction of wound size.
Official title: Comparison Between Povidone-Iodine and Ozonated Distilled Water Irrigation in the Management of Maxillofacial Space Infections (Randomized Controlled Clinical Trial)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
26
Start Date
2026-10-28
Completion Date
2027-02-28
Last Updated
2026-10-29
Healthy Volunteers
No
Conditions
Interventions
Incision and drainage + Povidone-iodine irrigation
Patients suffering from suprahyoid maxillofacial space infections will be treated with incision and drainage and then daily irrigation using povidone-iodine together with empirical antibiotics.
Incision and drainage + ozonated distilled
Patients suffering from suprahyoid maxillofacial space infections will be treated with incision and drainage then daily irrigation using ozonated distilled water together with empirical antibiotics.
Locations (1)
Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt
Alexandria, Azarita, Egypt