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Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude Regions
Sponsor: Diansan Su
Summary
Patients living in high-altitude areas naturally have lower blood oxygen levels. Those at high risk for Obstructive Sleep Apnea (OSA) face an even greater risk of low oxygen during painless gastrointestinal endoscopy. This multicenter study will randomly assign these patients to receive either High-Flow Nasal Oxygen (HFNC) or standard oxygen therapy during their procedure, aiming to find out if HFNC can safely and effectively reduce the risk of low oxygen events.
Official title: Effect of High-flow Nasal Cannula Oxygenation on the Incidence of Hypoxemia During Painless Gastrointestinal Endoscopy in Patients at High Risk for Obstructive Sleep Apnea Syndrome in High-altitude Regions: a Multicenter Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
430
Start Date
2026-11-02
Completion Date
2027-10-31
Last Updated
2026-10-29
Healthy Volunteers
No
Conditions
Interventions
High-flow nasal cannula Group
Using High-flow nasal cannula oxygenation
Regular Nasal Cannula Group
Using regular nasal cannula for oxygenation
Locations (3)
Haiyan County People's Hospital
Sanjiaocheng, Qinghai, China
Qinghai Provincial Traffic Hospital
Xining, Qinghai, China
The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China