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Toward Biomarker-Guided Fibromyalgia Treatment With Non-Invasive Vagus Nerve Stimulation
Sponsor: Massachusetts General Hospital
Summary
Fibromyalgia is a syndrome with clinical symptoms that affect multiple systems of the body. Although basic science research and clinical research trials have been carried out, the cause and the mechanism of fibromyalgia are still unknown. The goal of current medical treatment is to relieve symptoms and improve quality of life. Recent clinical and experimental studies have shown that stimulation of the vagus nerve has a potential to help pain syndromes. In this study, we aim to evaluate the effects of using transcutaneous vagus nerve stimulation (tVNS) on treating pain and other symptoms in fibromyalgia patients. We will do this by using the VagaCalm device.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
105
Start Date
2026-10-15
Completion Date
2029-08-31
Last Updated
2026-11-02
Healthy Volunteers
No
Conditions
Interventions
Transcutaneous Vagus Nerve Stimulation
30 minutes stimulation, twice per day for 6 weeks
Locations (1)
Massachusetts General Hospital
Boston, Massachusetts, United States