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Comparison of Ultrasound-Guided Erector Spinae Plane Block and Quadro-Iliac Plane Block in Elective Primary Unilateral Total Hip Arthroplasty
Sponsor: Uludag University
Summary
This prospective, single-center, randomized controlled, double-blind (participant and outcomes assessor) trial compares ultrasound-guided erector spinae plane block (ESPB) and quadro-iliac plane block (QIPB) in adult patients undergoing elective primary unilateral total hip arthroplasty (THA) under spinal anesthesia. Eighty patients will be randomized 1:1 to receive either block in addition to a standardized multimodal analgesia protocol. The primary outcome is cumulative opioid consumption (intravenous morphine equivalents, mg) during the first 24 postoperative hours. Secondary outcomes include quality of recovery (QoR-15), pain scores, opioid consumption at later time points, quadriceps strength, mobilization, patient satisfaction, and safety outcomes. It is hypothesized that QIPB will reduce 24-hour opioid consumption more than ESPB.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2026-10-31
Completion Date
2027-10-31
Last Updated
2026-11-03
Healthy Volunteers
No
Interventions
Quadro-Iliac Plane Block (QIPB)
Spinal anesthesia, then single-shot ultrasound-guided fascial plane block performed at the level of the iliac crest in the posterior plane of the quadratus lumborum muscle, with injection of 30 mL of 0.25% bupivacaine. Standard multimodal analgesia and morphine patient-controlled analgesia (PCA) are provided postoperatively.
Erector Spinae Plane Block
Spinal anesthesia, then single-shot ultrasound-guided lumbar erector spinae plane block targeting the L3 vertebral level, with injection of 30 mL of 0.25% bupivacaine. Standard multimodal analgesia and morphine PCA are provided postoperatively.