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Optimized Osteosynthesis: Bone Mineral Density Recovery in Mandibular Body Fractures Using Patient-Specific Versus Conventional Plates
Sponsor: Cairo University
Summary
The goal of this randomized controlled clinical trial is to evaluate and compare the bone mineral density (BMD) recovery following open reduction and internal fixation (ORIF) of mandibular body fractures using patient-specific plates versus conventional plates. Bone density at the fracture site will be quantified using Hounsfield Units (HU) on computed tomography (CT) scans. The main question it aims to answer is: Do patient-specific plates provide a superior recovery of bone mineral density at the fracture site compared to conventional plates in patients undergoing fixation for mandibular body fractures?
Official title: Optimized Osteosynthesis: A Comparative Analysis of Bone Mineral Density Recovery in Mandibular Body Fractures Using Patient-Specific Versus Conventional Plates (A Randomized Controlled Clinical Trial)
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
26
Start Date
2026-10-12
Completion Date
2028-01
Last Updated
2026-10-29
Healthy Volunteers
No
Conditions
Interventions
Open reduction and Internal fixation of a mandibular body fracture
Patient-Specific titanium plates designed using virtual 3D planning software and fabricated via computer-aided manufacturing to match the patient's precise pre-injury mandibular anatomy.
Open reduction and Internal fixation of a mandibular body fracture
Commercially available, standard stock titanium plates will be adapted and bent manually by the surgeon during the operation to fit the patient's mandibular anatomy.
Locations (1)
Faculty of Dentistry- Cairo University
Cairo, Giza Governorate, Egypt