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COMPLETED
NCT07905690
NA

Adaptations in the Biceps Brachii Muscles to Different Modalities of Resistance Training

Sponsor: Umeå University

View on ClinicalTrials.gov

Summary

This study examined how two types of resistance training affect the biceps muscle over six weeks in healthy young men. Participants performed either low-repetition, heavy-load training designed to improve maximal strength or high-repetition training designed to improve muscular endurance. Training was supervised and performed twice weekly. Researchers measured arm strength and muscular endurance before and after training. They also collected small samples of biceps muscle tissue to examine muscle-fibre characteristics and changes in muscle proteins. These protein measurements were intended to identify early changes in muscle that may occur before visible changes in muscle size or measurable improvements in performance. The study found no clear differences between the two training approaches in strength, endurance, muscle-fibre size, or muscle-fibre type after six weeks. However, the two programs were associated with different patterns of change in muscle proteins. These findings may help researchers understand the early biological processes through which different types of resistance exercise affect skeletal muscle. This was a small exploratory study, so the results may not apply to other populations or longer training programs.

Official title: Initial Adaptations in the Biceps Brachii Muscles to Different Modalities of Resistance Training: A Randomized Top-down Proteomic Pilot Study

Key Details

Gender

MALE

Age Range

18 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2004-09-01

Completion Date

2026-06-29

Last Updated

2026-10-29

Healthy Volunteers

No

Interventions

BEHAVIORAL

Strength training

A supervised, isolated biceps-brachii resistance-training intervention delivered twice weekly for six weeks. Participants performed bilateral preacher curls (Scott curls) with free weights on an EZ bar, using a standardized range of motion from full elbow extension to 135 degrees of elbow flexion.