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Ultrasound-guided Microwave Ablation of Benign Thyroid Nodules
Sponsor: Chinese University of Hong Kong
Summary
The goal of this clinical trial is to learn if microwave ablation of benign thyroid nodules under local anaesthesia is a safe and effective procedure compared to open thyroidectomy. The main questions it aims to answer are: Dose microwave Ablation effectively cause shrinkage of thyroid nodules? Can ablation of selective area of nodules be safely performed under ultrasound guidance, avoiding critical structures including recurrent laryngeal nerve, major vessels and trachea? Researchers will recruit subjects with symptomatic benign thyroid nodules for Microwave Ablation. Participants will: Undergo ultrasound guided Microwave Ablation of benign thyroid nodules. Visit the clinic at post operation 2-week, 3-month, 6-month, 12-month, 2-year and 3-year for checkups and tests. Fill in questionnaire at each clinic visit for pain, pressure symptoms, cosmetic overall satisfaction in Visual Analog Scale.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2023-08-31
Completion Date
2029-05-31
Last Updated
2026-11-02
Healthy Volunteers
No
Conditions
Interventions
ultrasound-guided percutaneous microwave ablation (MWA)
Under ultrasound guidance, the microwave electrode was inserted targeted to the nodule. Ablation is carried out one axial plane at a time, from inferior to superior aspect of the targeted lesion. Within each axial plane, ablation is performed from deep to superficial manner to prevent bubble generated by the ablation from hindering ultrasound examination. The extent of the ablated zone is determined real-time by the echogenic changes around the electrode. Ablation will be away from important structure, including major vessels, recurrent laryngeal nerve and trachea. During the procedure, the patient's vital signs including O2 saturation, blood pressure and heart rate would be monitored. Operative procedures, difficulties encountered (if any) and operation time will be documented.
Locations (1)
The Chines University of Hong Kong
Shatin, Hong Kong