Clinical Research Directory

Topical Terbinafine Versus Hydrocortisone Combined With Oral Itraconazole for Seborrheic Dermatitis

Sponsor: Can Tho University of Medicine and Pharmacy

Summary

The goal of this clinical trial is to compare two creams used together with oral itraconazole in adults with moderate-to-severe seborrheic dermatitis. The main question it aims to answer is: does terbinafine 1% cream give lower disease severity than hydrocortisone 1% cream at the end of a 2-week course of oral itraconazole? Participants took oral itraconazole 100 mg twice daily for 2 weeks and applied either terbinafine 1% cream or hydrocortisone 1% cream twice daily for 4 weeks. Disease severity (Seborrheic Dermatitis Area and Severity Index, SDASI), itching, burning and local side effects were assessed at baseline, week 2 and week 4.

Official title: Topical Terbinafine 1% Versus Hydrocortisone 1% Combined With Oral Itraconazole for Moderate-to-Severe Seborrheic Dermatitis: A Two-Centre Non-Randomized Controlled Trial

Key Details

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Interventions

Locations (2)