Clinical Research Directory

Inclusion Criteria: * Over 18 years of age * Hospitalized in an intensive care unit * Participants who have experienced organ failure requiring organ support (invasive mechanical ventilation, vasopressor amines, continuous renal replacement therapy, veno-venous or arteriovenous extracorporeal circulation), regardless of the duration of such support. * Participants eligible for daily physical therapy * Confirmed muscle weakness (MRC score strictly below 48/60) * Able to sit on the edge of the bed without support * Unable to walk independently * Have provided written consent * Enrolled in a social security program Exclusion Criteria: * Hemodynamic instability requiring the use of vasopressor amines * Respiratory failure requiring continuous support * Impaired consciousness, confusion, or a neurological condition that prevents compliance with treatment * Orthostatic hypotension * Skin lesion at the device site * Perineal skin lesion * Participants under legal guardianship * Lower limb amputation * Pregnant women * Participation in another interventional study involving nutrition or rehabilitation * Weight greater than 100 kg * Height \> 195 cm * Hip flexion greater than 20° * Knee flexion greater than 20° * Inability to achieve 0° passive dorsiflexion of the ankle * Spasticity \> 3 on the Ashworth scale * Orthostatic hypotension upon standing * Poor tolerance of the orthosis (hemodynamic issues, skin lesions, etc.) * Hip flexion greater than 20° * Knee flexion greater than 20° * Passive ankle dorsiflexion at 0° impossible * Spasticity \> 3 on the Ashworth scale